Tijaabada Dhiigga Ayaa Caawin Ka Bixin Doonta Kansarka Naasaha, Ayaa Lagu Yiri Daraasad Dhawaan Soo Baxday

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Kansarka naasaha waa nooca ugu badan ee kansarka maqaarka. Waxaa la sheegay inuu ka mid yahay noocyada ugu badan ee kansarka ee saameeya aadanaha, gaar ahaan tobankii sano ee la soo dhaafay. Hindiya oo keliya, in kabadan 1 milyan oo kiis oo kansarka naasaha ah ayaa la soo tabiyaa sannad kasta.

Warbixintii ugu dambeysay, qiyaastii 252, 710 baaritaano cusub ayaa laga filayaa dumarka, iyadoo ku dhowaad 40,610 haween ah ay u badan tahay inay u dhintaan cudurka. Kansarka naasaha kuma koobna dumarka, maxaa yeelay ragga ayey saameyn ku yeelan kartaa. In kabadan 9,500 oo qof ayaa raadiya daryeelka kansarka naasaha sanad kasta ku dhowaad 1,500 oo qof ayaa mara qalliinka kansarka naasaha sanad kasta ^[1] .

Kansarka naasuhu wuxuu soo baxaa marka unugyada naasuhu bilaabaan inay u koraan si aan caadi ahayn, taas oo markaa si dhakhso leh uga tarma tan unugyada caafimaadka qaba oo ay sii wadato tarmo, taas oo keenaysa horumarinta tiro ama buro ^[laba] . Caadi ahaan, kansarka naasaha ayaa la ogaadaa marka calaamado ama astaamo ay soo baxaan oo la baaro iyadoo la kaashanayo baaritaanka iyo nidaamyada sida baaritaanka naasaha, raajada naasaha , Ultrasound naasaha iwm.

Si kastaba ha noqotee, daraasad dhowaan la sameeyay ayaa lagu sheegay in tijaabada dhiigga ee casriga ahi ay gacan ka geysan karto in goor hore la ogaado kansarka naasaha.

Tijaabada Dhiiggu Waxay Caawinkartaa Soo Saarida Kansarka Naasaha 5 Sano Kahor Calaamadaha muuqda

Mid ka mid ah halista iyo dhibaatooyinka ugu waaweyn ee kansarka waa ogaanshaha goor dambe. Marka xaaladdu ku faafto meelo kale, heerka badbaadadu aad ayuu u hooseeyaa iyada oo suurtagalnimada soo noqoshada ^[3] .

Si kastaba ha noqotee, ogaanshaha hore iyo daaweynta wax ku oolka ah waxay gacan ka geysan kartaa hagaajinta heerka dhimashada. Laakiin marka laga hadlayo kansarka naasaha, ogaanshaha hore ee dabiiciga ah wuu xadidan yahay maadaama uusan had iyo jeer soo saarin calaamado muuqda marxalad hore, taas oo u horseedi karta ogaanshaha xilli dambe ee saameyn ku yeelan kara waxtarka daaweynta.

Daraasad dhowaan ay sameeyeen cilmi baarayaal ka socda Jaamacadda Nottingham ee Boqortooyada Ingiriiska ayaa cadeeyay in tijaabada dhiigga ee lagu baaro jiritaanka unugyada jirka qaarkood ay ka caawin karto in lagu ogaado kansarka naasaha goor hore iyo si fudud ^[4] .

Tijaabadu Waxay Soo Saari Kartaa Awoodaha Gawaarida

Cilmi baarayaashu waxay sii wadeen inay sharraxaan habka baaritaanka dhiigga iyagoo sharraxaya in markii kansarku jiro, jirkaaga uu soo saaro antigens oo kiciya jawaab celinta jirka. Tani, markeeda, waxay keentaa in habka difaaca jirka uu ula falgalo walxaha isagoo sii daayo unugyada difaaca jirka, ka dibna waxaa lagu ogaan doonaa baaritaanka dhiigga wuxuuna muujinayaa inuu jiro iyo in kale kansarka naasaha.

Ugu horreyntii, cilmi baarayaashu waxay soo saareen qaybo ka mid ah antigens-ka burooyinka la xiriira (TAAs) oo gaar u ah kansarka naasaha kaas oo gacan ka geystay fahamka jiritaanka autoantigens ee dhiigga ee la xidhiidha jawaab-celinta kansarka naaska ee gaarka u ah TAAs. ^[5] .

Mid ka mid ah cilmi baareyaasha Daniyah Alfattani ayaa yiri, 'Natiijooyinka daraasaddeenna waxay muujiyeen in kansarka naasuhu uu kicinayo unugyada jirka ee jirka ka hortaga unugyada antigens-ka la xiriira burooyinka gaarka ah. Waxaan awoodnay inaan ku ogaanno kansarka si sax ah oo macquul ah annaga oo aqoonsanayna qalabkan isdifaaca dhiigga ', waxaana sidoo kale ku nuuxnuuxsannay baahida loo qabo in la horumariyo oo la sii adkeeyo baaritaanka dhiigga ^[6] .

Daraasadu Waxay Muujinaysaa Natiijooyin rajo leh

Cilmi baarayaashu waxay ku faraxsan yihiin natiijada daraasadda maxaa yeelay natiijooyinka ayaa dhiirrigelinaya waxayna muujinayaan inay suurtagal tahay in la ogaado calaamadda kansarka naasaha hore. 'Marka aan kor u qaadno saxsanaanta baaritaanka, markaa waxay fureysaa suurtagalnimada in la isticmaalo baaritaanka dhiigga ee fudud si loo wanaajiyo ogaanshaha hore ee cudurka', ayuu yiri cilmibaaraha ^[6] .

Daraasadda oo leh jawaabeyaal ka badan 90, waxaa loo qaadan karaa in natiijooyinka ay yihiin kuwo macquul ah oo sax ah iyo baaritaanka dhiigga ee hal-abuurka ah wuxuu faa'iido u yeelan karaa caawinta khubaro caafimaad iyo dhakhaatiirtu waxay ogaadaan jiritaanka kansarka naasaha illaa 5 sano kahor intaan astaamo muuqda la arkin.

Xusuusin Dhameystiran ...

Daraasaddan oo soo saaraysa natiijooyin wax ku ool ah, cilmi-baarayaashu waxay dejinayaan ballaarinta aagga daraasadda maxaa yeelay baaritaanka dhiigga ee hore ee lagu ogaado kansarka naasaha ayaa noqon doona mid kharash-ku-ool ah, sidoo kale wuxuu noqon doonaa mid wax ku ool ah iyo sidoo kale hab fudud oo baaris ah marka loo eego tallaabooyinka jira ^[7] . Tijaabooyin la mid ah ayaa loogu talagalay noocyada kale ee kansarka, oo ay ku jiraan sambabada, ganaca, malawadka, iyo kansarka beerka.

1. [1]Lauren, S. & Cassell, M. Qalliinka naasaha, Cusbitaalka Lenox Hill, Magaalada New York ee Booliska Alice, MD, agaasimaha gobolka Westchester, qalliinka naasaha, Machadka Kansarka ee Northwell Health, Sleepy Hollow, NY NCRI (National Cancer Research Institute, UK), war-saxaafadeed, Nov. 2, 2019
2. [laba]Spadafora, C., Sciamanna, I., De Luca, C., Sinibaldi-vallebona, P., Guadagni, F., Schumann, G., & Garaci, E. (2019). Mareykanka Codsiga Patent No. 15 / 564,089.
3. [3]Spadafora, C., Sciamanna, I., De Luca, C., Sinibaldi-Vallebona, P., Guadagni, F., Schumann, G., & Garaci, E. (2019). Mareykanka Codsiga Patent No. 10 / 214,591.
4. [4]Yadav, S., Kashaninejad, N., Masud, M. K., Yamauchi, Y., Nguyen, N. T., & Shiddiky, M. J. (2019). Autoantibodies sida ogaanshaha iyo ogaanshaha cudurka kansarka biomarker: farsamooyinka ogaanshaha iyo habab. Biosensors iyo Bioelectronics, 111315.
5. [5]Jiang, X. H., Yao, Z. Y., Is, X., Zhang, J. B., Xie, K., Chen, J., ... & Yie, S. M. (2019). Muhiimadda caafimaad ee plasma anti-TOPO48 autoantibody iyo dhiig badbaado-muujinta unugyada kansarka wareega ee bukaanka qaba marxaladda hore ee kansarka jirka. Arkiifiyada cudurada haweenka iyo dhalmada, 299 (1), 229-237.
6. [6]Seluk, L., Taliansky, A., Yonath, H., Gilburd, B., Amital, H., Shoenfeld, Y., & Dhaqdhaqaaqa, S. (2019). Shaashad ballaaran oo loogu talagalay baaritaanka cudurka 'paraneoplastic neurological autoantibodies ogaanshaha iyo qiyaasaha saadaalinta. Immunology Clinical, 199, 29-36.
7. [7]Khayeka-Wandabwa, C., Ma, X., Cao, X., Nunna, V., Pathak, J. L., Bernhardt, R., ... & Bureik, M. (2019). Dejinta xuubka Plasma ee CYP4Z1 iyo CYP19A1 iyo ogaanshaha anti-CYP19A1 autoantibodies ee aadanaha. Immunopharmacology caalami ah, 73, 64-71.

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