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Hoyga Caafimaadka Cilladaha ayaa daaweeya Cilladaha daaweeya oi-Neha Ghosh By Neha Ghosh Abriil 4, 2019

Vitiligo waa xaalad isdifaac ah oo unugyo cadcad ay ku soo baxaan maqaarka. Hindiya gudaheeda, dhacdooyinka loo yaqaan 'vitiligo' waa min 0.25 ilaa 2.5%. Rajasthan iyo Gujarat ayaa leh cudurka ugu badan ee xaaladdan ^[1] .

Waa maxay Vitiligo?

Melanocytes, unugyada sameeya midabka maqaarka, ayaa mas'uul ka ah midabka maqaarkaaga, midabka indhaha, iyo midabka timaha. Marka melanocytes-ka la baabi'iyo, balastarro cad ayaa ka soo baxa maqaarka, oo loo yaqaan 'vitiligo' ^[laba] . Vitiligo wuxuu ku dhacaa meelaha kale ee jirka sida gacmaha, wejiga, qoorta, jilbaha, cagaha iyo xusullada.

Vitiligo ma aha mid la is qaadsiin karo waana natiijada sababaha hidda-wadaha, arrimaha deegaanka ama yaraanta nafaqooyinka qaarkood.

Calaamadda ugu horreysa ee vitiligo waa balastar si tartiib tartiib ah ugu soo muuqanaysa aagga maqaarka iyadoo timuhu isu beddelayaan caddaan. Calaamadaha kale ayaa ah in timo madaxu ku dhicis noqdaan madaxaaga, sunnayaasha, gadhka iyo baarkooda, midab luminta unugyada kujira gudaha sankaaga iyo afkaaga, iyo midab luminta qeybta hoose ee isha.

Daaweynta loo yaqaan 'vitiligo' waxay qaadataa waqti si loo muujiyo natiijooyin wax ku ool ah. Hadday tahay daaweyn caadi ah ama dabiici ah, waxay qaadan kartaa 6 bilood illaa laba sano.

Laga soo bilaabo waqtiyadii hore, noocyo kala duwan oo geedo ah ayaa loo isticmaali jiray daaweynta vitiligo.

1. Ginkgo biloba

Dhowrkii sano ee la soo dhaafay, waxyaabaha laga soo saaro ginkgo biloba ayaa loo isticmaalay daaweynta vitiligo sababta oo ah ginkgo biloba waxay leedahay lahaansho anti-bararka, difaaca jirka, iyo antioxidant. Xogta daraasadda waxay muujineysaa in ginkgo biloba ay maamusho waxqabadka vitiligo waxayna keentaa sumcadda maqaarka cad haddii loo isticmaalo daweynta kale sida sawir-qaadista iyo corticosteroids ^[3] . Daraasad kale ayaa sidoo kale muujineysa waxtarka ka soo baxa geedaha marka kalidaa la maamulo ^[4] .

Natiijooyinka dib-u-celinta waxay ku kala duwanaan kartaa iyadoo kuxiran waxyaabaha sida noocyada kala duwan ee laga soo saaro ginkgo biloba, muddada daaweynta, iyo tirada qiyaasaha maalintii.

Daawada waxaa loo qaabeeyey kaniini oo qiyaasta maalin kasta waa 120 mg maalintii. Waa in afka lagu qaataa hal ilaa saddex jeer maalintii in ka badan 3 bilood.

2. Cirrida

Turmeric waxa ku jira maadada polyphenol ee loo yaqaan curcumin taas oo la ogyahay inay ku jirto antioxidant, anti-bararka, antiviral, antibacterial, antiproliferative and antifungal properties. Sida laga soo xigtay daraasad dhowaan, kareem tetrahydrocurcumide ayaa loo isticmaalay nb - UVB daaweynta vitiligo natiijooyinka waxay muujiyeen sumcad ka wanaagsan. ^[5] .

3. Shaah cagaaran

Caleenta shaaha cagaaran waxay hodan ku tahay polyphenol antioxidants. Soosaarida caleen shaaha cagaaran waxay u shaqeysaa sida anti-bararka, antioxidant, iyo wakiilada immunomodulatory kuwaas oo la xaqiijiyay inay waxtar u leeyihiin daaweynta vitiligo iyadoo la joojinayo cadaadiska oksida ee qaybta melanocyte ^[6] .

Soosaarida caleen shaaha cagaaran waxaa lagu maamuli karaa hadal ahaan iyo maad ahaanba.

4. Capsaicin

Basbaaska Chilli waxaa ku jira maadada firfircoon ee loo yaqaan 'capsaicin' oo ka kooban antioxidant iyo anti-bararka guryaha oo u shaqeeya sidii daaweyn loogu talagalay vitiligo ^[7] .

5. Aloe vera

Aloe vera waxay daaweyn kartaa cudurrada maqaarka ee kala duwan oo ay ku jiraan cilladaha midabka maxaa yeelay waxay ka kooban tahay fiitamiinnada antioxidant sida fitamiin A, fitamiin C, fitamiin B12 iyo folic acid. Soosaarka Aloe vera sidoo kale wuxuu ka kooban yahay zinc, copper, iyo chromium oo laga yaabo inay taageeraan sumcadda maqaarka ^[8] .

Jel ka soo saar caleenta aloe vera oo mari aagga ay dhibaatadu gaadhay.

6. Muskmelon

Soosaarida Muskmelon waxaa ka buuxa antioxidants ka hortaga melanocytes deconstruction oo uu sababo diiqadda oksida. Daraasad ayaa muujisay waxtarka sameynta jel ee ay ku jiraan phenylalanine, soosaarida muskmelon, iyo acetylcysteine ee ku jirta vitiligo. Daaweyntu waxay sii socotey toddobaadyada 12 boqolkiiba 75 ee sumcadda ayaa lagu muujiyey bukaannada ^[9] .

7. Picrorhiza kurroa

Picrorhiza kurroa, sidoo kale loo yaqaan kutki ama kutaki, waa warshad daawo ah oo laga helo Himalayas. Waxay ka kooban tahay hepatoprotective, antioxidant iyo immunomodulatory properties. Daraasad la sameeyay ayaa muujisay awooda xoogan ee Picrorhiza kurroa oo loo adeegsado fototherapy daaweynta vitiligo. Waxaa la maamuli jiray laba jeer maalintii hadal ahaan muddo 3 bilood ah ^[10] .

8. Pyrostegia Venusta

Pyrostegia venusta waa geedo loo isticmaalo daaweynta vitiligo. Waxay ka kooban tahay antioxidant, anti-bararka iyo melanogenic guryaha. Waxaa laga helaa Koonfurta Baraasiil, halkaas oo qaababka jirka la mariyo loo isticmaalo daaweynta vitiligo ^{kow iyo toban} .

9. Khellin

Tan iyo wakhtiyadii hore ee Masaarida, khellin waxaa loo isticmaali jiray daawo dhaqameed oo dadka lagu daaweeyo cuduro badan sida dhagxaanta kalyaha, wadna xanuunka, vitiligo, neefta neefta iyo cudurka psoriasis. Khellin loo isticmaalo oo ay weheliso daawada loo yaqaan 'UVA phototherapy' ayaa la muujiyey inay wax ku ool u tahay daaweynta cudurka 'vitiligo'. Khellin wuxuu ku shaqeeyaa kicinta melanocytes badashada iyo melanogenesis ^[12] .

10. Polypodium leucotomos

Polypodium leucotomos waa fern kulayl ah oo lagu heli karo qaabka kaabsoosha iyo kareemka la mariyo. Waxaa laga helaa gobollada kulaylaha iyo kuleylka ah ee Ameerika. Soosaarida Polypodium leucotomos waxay caan ku tahay astaamaha antioxidant-ka iyo sawir-qaadeyaasha waxaana loo isticmaalaa daaweynta cudurrada maqaarka ee kala duwan. Polypodium leucotomos ayaa loo isticmaalay iyada oo ay weheliso daawaynta fototerapi ee bukaanka vitiligo ^[13] .

Fiiro gaar ah: Kahor intaadan isticmaalin daawooyinkaan dhirta dabiiciga ah, waxaa ugufiican inaad kala tashato dhaqtar qiyaasta saxda ah iyo inaad si sax ah u codsato maxaa yeelay waxaa laga yaabaa inay yeeshaan waxyeelo aanad ka warqabin.

Eeg Tixraaca Maqaalka

[1]Vora, R. V., Patel, B. B., Chaudhary, A. H., Mehta, M. J., & Pilani, A. P. (2014). Daraasad caafimaad oo ku saabsan Vitiligo oo ku taal miyiga Gujarat. Joornaalka Hindiya ee dawada bulshada: daabacaad rasmi ah ee Ururka Hindida ee Ka Hortagga & Caafimaadka Bulshada, 39 (3), 143-146.
[laba]Yamaguchi, Y., & Maqalka, V. J. (2014). Melanocytes iyo cuduradooda. Aragtida qaboobaha xilliga qaboobaha ee dawada, 4 (5), a017046.
[3]Cohen, B. E., Elbuluk, N., Mu, E. W., & Orlow, S. J. (2015). Daaweynta habdhiska ah ee loo yaqaan 'vitiligo': dib u eegis. Joornaalka Mareykanka ee maqaarka maqaarka, 16 (6), 463-474.
[4]Parsad, D., Pandhi, R., & Juneja, A. (2003). Wax ku oolnimada afka Ginkgo biloba ee daaweynta xaddidan, si tartiib tartiib ah u faafisa vitiligo. Cilmiga maqaarka iyo takhasuska: maqaarka tijaabada, 28 (3), 285-287.
[5]Asawanonda, P., & Klahan, S. O. (2010). Kareemka 'Tetrahydrocurcuminoid cream' oo lagu daray bartilmaameedka cidhiidhiga ah ee loo yaqaan 'UVB phototherapy' ee loo yaqaan 'vitiligo': daraasad horudhac ah oo la kantaroolay oo la kala sooco. Photomedicine iyo qalliinka laser, 28 (5), 679-684.
[6]Jeong, Y. M., Choi, Y. G., Kim, D. S., Park, S. H., Yoon, J. A., Kwon, S. B., ... & Park, K. C. (2005). Saameynta cytoprotective ee soosaarida shaaha cagaaran iyo quercetin ee ka dhanka ah walbahaarka oksidheeyaha ee kudhaca hydrogen peroxide. Archives of pharmacal research, 28 (11), 1251.
[7]Becatti, M., Prignano, F., Fiorillo, C., Pescitelli, L., Nassi, P., Lotti, T., & Taddei, N. (2010). Ku lug lahaanshaha Smac / DIABLO, p53, NF-kB, iyo MAPK waddooyinka apoptosis ee keratinocytes oo ka yimaada maqaarka vitiligo perilesional: waxyeelada ilaalinta ee curcumin iyo capsaicin.
[8]Tabassum, N., & Hamdani, M. (2014). Dhirta loo isticmaalay in lagu daaweeyo cudurada maqaarka Dib u eegista Pharmacognosy, 8 (15), 52-60
[9]Buggiani, G., Tsampau, D., Hercogovà, J., Rossi, R., Brazzini, B., & Lotti, T. (2012). Waxtarka bukaan-socodka ee qaabka cusub ee loo yaqaan 'vitiligo': marka la barbardhigo qiimeynta hababka daaweynta ee kala duwan ee bukaanada 149.Dermatologic therapy, 25 (5), 472-476.
[10]Gianfaldoni, S., Wollina, U., Tirant, M., Chernev, G., Lotti, J., Satolli, F.,… Lotti, T. (2018). Xarumaha Dhirta ee Daaweynta Vitiligo: Dib u Eegis. U furitaanka marinka Macedonia ee cilmiga caafimaadka, 6 (1), 203-207
kow iyo tobanMoreira, C. G., Carrenho, L. Z. B., Pawloski, P. L., Soley, B. S., Cabrini, D. A, & Otuki, M. F. (2015). Caddaynta hore ee daaweynta ee loo yaqaan 'Pyrostegia venusta' ee daaweynta 'vitiligo' Joornaalka 'ethnopharmacology', 168, 315-325.
[12]Carlie, G., Ntusi, N. B. A., Hulley, P. A., & Kidson, S. H. (2003). KUVA (khellin iyo ultraviolet A) waxay kicisaa faafitaanka iyo melanogenesis ee melanocytes-ka caadiga ah ee bini-aadamka iyo unugyada melanoma ee ku jira fitamiinnada. British Journal of Dermatology, 149 (4), 707-717.
[13]Nestor, M., Bucay, V., Callender, V., Cohen, J. L., Sadick, N., & Waldorf, H. (2014). Polypodium leucotomos oo ah Daaweyn Dheeraad ah oo ah Xanuunada Pigmentary. Joornaalka maqaarka daaweynta iyo bilicsanaanta, 7 (3), 13-17.